Gastric neoplasms and pepsinogen phenotypes
نویسندگان
چکیده
منابع مشابه
The serum pepsinogen levels for risk assessment of gastric neoplasms
To decrease the gastric cancer related mortality rate, endoscopic screening is widely performed in Korea. However, a precise method for identifying those at a high risk of gastric neoplasms has not been established. This study aims to evaluate serum pepsinogen (PG) levels for risk assessment of gastric neoplasms. Between August 2014 and March 2016, a total of 398 subjects, including 87 with gas...
متن کاملLauwers-Early gastric neoplasms
Despite a marked decline in incidence in the West and some decrease in the East, gastric cancer remains a significant cause of morbidity and cancer related deaths worldwide. The prevalence of gastric cancer is closely related to prevalence of Helicobacter pylori infection and shows wide geographic variation. Subsequent chronic gastritis, atrophy, and intestinal metaplasia are lesions that confe...
متن کاملPepsinogen synthesis and secretion in isolated gastric glands.
De novo synthesis of pepsinogen was shown in isolated rabbit and human gastric glands after incubation of the glands in a 14C labelled amino acid enriched minimum Eagles medium. At regular intervals, glands and medium were separated and analysed by polyacrylamide gel electrophoresis. Newly synthesised pepsinogen was shown by autoradiography. Incorporation of 14C labelled amino acids was detecte...
متن کاملGastric cancer detection using gastric juice pepsinogen and melanoma-associated gene RNA.
OBJECTIVES To develop a new method for gastric cancer detection with gastric juice using melanoma-associated gene (MAGE) RNA and pepsinogen (PG). METHODS In total, 183 gastric juice and paired serum specimens were obtained from 134 patients with gastric cancer and 49 healthy individuals. The gastric juice specimens were analyzed with MAGE A1 to A6 nested reverse transcription-polymerase chain...
متن کاملPAR-2 modulates pepsinogen secretion from gastric-isolated chief cells.
In the present study, we investigated whether activation of protease-activated receptor type 2 (PAR-2) with SLIGRL (SL)NH2, a short mimetic agonistic peptide, directly stimulates pepsinogen secretion from gastric-isolated, pepsinogen-secreting (chief) cells. Immunostaining of gastric-dispersed chief cells with a specific anti-PAR-2 antibody demonstrated expression of PAR-2 receptors on membrane...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1982
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1982.195